Integration with Chameleon is available for a number of popular web frameworks.
Chameleon is the default template engine for the Pyramid framework. See the section on Zope Page Templates in the documentation for that project.
If your application uses the CMF content management framework (including Plone), the cmf.pt package contains the required support.
For applications based on the Zope Toolkit (ZTK), install and include the z3c.pt package.