Go to the "Tools" menu, and "Batch blast". On the "batch blast" dialog box
press the "Load files" button and select all the files you want to blast.
Press the "Load reference" button and select the reference file you created
earlier. If you selected "Process hotpixels only" on the Settings dialog
you don't have to load a reference file.
Finally, press the "Blast" button. You'll see various progress indicators
as the blasting takes place. The original images are left unmodified;
processed files will be located in a subdirectory called dbblast by default
or another user selected output directory.
That's all there is to it. Pretty simple!